Regulatory T Cells in the Spotlight: Nobel 2025 Honors Brunkow, Ramsdell & Sakaguch

In his article “The Riot Police of the Immune System,” Jon Garay celebrates the winners of the 2025 Nobel Prize in Physiology or Medicine — Shimon Sakaguchi, Mary E. Brunkow, and Fred Ramsdell — for discovering regulatory T cells. María Mittelbrunn explains how these “immune riot police” keep our defenses in check, preventing autoimmune diseases while allowing efficient protection against infections and cancer. The piece not only congratulates the laureates for their crucial contribution to biomedical science but also highlights the delicate balance of our immune response, a harmony that keeps us healthy.

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