Imagine a world
immune to aging

How does the Immune System
controls aging?

We have been pioneers proposing that the immune system, particularly T cells, controls tissue senescence and the onset of age-related diseases. We are now investigating how the immune system contributes to systemic senescence as well as to the general aging process. Would the rejuvenation of the immune system compartment suffice to delay organismal aging or at least some of its manifestations? An affirmative response to this question might have vast consequences for  improving healthy aging.

At Mittelbrunn Scientific Research, we aspire to rejuvenate the immune system using cutting-edge nutritional, genetic, cellular, and pharmacological strategies, aiming to prevent chronic inflammation and age-related diseases, thereby redefining the concept of healthy aging.

Featured Publications

Cytotoxic CD4+ T cells in the bone marrow compromise healthy ageing by enhancing granulopoiesis

T cells with dysfunctional mitochondria induce multimorbidity and premature senescence

Main funders

Latest News

Dialogue on Longevity and Aging between Dr. Manuel Collado and Dr. Maria Mittelbrunn organized by AFundacion and Senescel in Santiago de Compostela

Dialogue on longevity and aging"organized thanks to Afundacion and SENESCEL

Manuel Wins Presentation Award at Oral Gut Conference at Karolinska Institute!

Congratulations to Manuel for winning Oral Presentation Award at the OralGut Conference 2

Donate

With your support and that of other generous donors, Mittelbrunn´s Lab will have the necessary tools, personnel, and resources to spearhead the battle against age-associated diseases and conditions. Together, we can promote healthy aging and harness the power of the immune system to extend longevity.